Knock Outs bloom on new growth, so old, dead, or broken canes should be.
Growing Roses in Arkansas Garden Guides.
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These roses tend to bloom on old wood. It’s fine to remove winter-killed branches or otherwise damaged wood early in the year, but defer your annual pruning until summer, after the peak of bloom.

Prune to remove undesirable canes and to shape and train growth. Side branches tend to. Knock Out Roses Pruning Steps: To maintain a size of 3–4’ w x 3–4’ h, Knock Out Roses should be cut back once a year to 12” high. Check your rose bush from time to time in late winter/early spring, and when you start to see new shoots growing from the canes on your rose bush, that’s a good sign that it’s time to prune.